QBO is not a web-enabled copy of the Desktop version. It is important, primarily, to understand that, although QuickBooks Desktop and QBO share the name “QuickBooks,” they are not related. Identifying which features are needed from the software will determine which option is best.
My response to that inquiry is that they are different products and fit different situations.
Businesses that use QuickBooks often ask about the differences between QuickBooks Desktop and QuickBooks Online (QBO), which was introduced in 2000.